Pontificia Universidad Católica de Chile Pontificia Universidad Católica de Chile
Pedreschi F., Mariotti M.S. and Granby K. (2014)

Current issues in dietary acrylamide: formation, mitigation and risk assessment.

Revista : Journal of the Science of Food and Agriculture
Volumen : 94
Número : 1
Páginas : 9-20
Tipo de publicación : ISI Ir a publicación


Acrylamide (AA) is known as a neurotoxin in humans and it is classified as a probable human carcinogen by the International Agency of Research on Cancer (IARC, 1994). AA is produced as by-product of Maillard reaction in starchy foods processed at high temperatures (> 120 °C). This review includes the investigation of AA precursors, mechanisms of AA formation and AA mitigation technologies in potato, cereal and coffee products. Additionally most relevant issues of AA risk assessment are discussed. New technologies tested from laboratory to industrial scale face as a major challenge to diminish the AA content of browned food, still maintaining their attractive organoleptic properties. Reducing sugars such as glucose and fructose are the major contributors to AA in potato based products. On the other hand, the limiting substrate of AA formation in cereals and coffee is the free amino acid asparagine.
For some products the additions of glycine or asparaginase reduce the AA formation during baking. Since, for potatoes the limiting substrates is reducing sugars, increases in sugar contents in potatoes during storage then introduce some difficulties and potentially quite large variations in the AA content of the final products. Sugars in potatoes may be reduced by blanching.
The levels of AA in different foods show large variations, and no general upper limits for content are easily practically to comply with since some formation will always occur. Current policy is that practical measures should be taken voluntarily to reduce AA formation in vulnerable foods since AA is considered as a health risk at the concentrations found in foods.